HMO & BRAIN HEALTH

Human milk oligosaccharide supports brain functions directly through:

  • Memory improvement
    by strengthening synapses and LTP (long-term potentiation) in the hippocampus.
  • Brain development
    when comparing children who were fed beast milk or HMO supplemented formula against their non supplemented peers.
  • Protect against brain damage by stroke and aiding brain recovery
    as published in research papers

Gut-brain connection

Did you know that microorganisms in the intestines help the brain and gut communicate?

This is known as the Gut-brain connection! This is might also be the reason why we get indigestion when we are stressed or have a lot to think about. And when we have indigestion, chances are that we might also have a headache! 

Human Milk Oligosaccharide can play a part in alleviating this! 95% of our serotonin, the neurotransmitter in charge of emotions, sleep etc, is produced in the gut! Human Milk Oligosaccharide stimulates the production of tryptophan, which serotonin is made from!

References

  • Brain ganglioside and glycoprotein sialic acid in breastfed compared with formula-fed infants American Journal of Clinical Nutrition, 2003
  • Fucose and fucosyllactose enhance in-vitro hippocampal long-term potentiation
     Brain Research 725 (1996) 276-280
  • Effects of a human milk oligosaccharide, 2′-fucosyllactose, on hippocampal long-term potentiation and learning capabilities in rodents
    Journal of Nutritional Biochemistry 26 (2015) 455–465
  • 2′-Fucosyllactose Attenuates Particulate Matter-Induced Inflammation via Inhibition of Hypoxia-Inducible Factor in Keratinocytes Biol. Pharm. Bull. 42, 1620–1627 (2019)
  • Influence of 2'-fucosyllactose and galacto-oligosaccharides on the growth and adhesion of Streptococcus mutans British Journal of Nutrition (2020), 124, 824–831
  • 2’-fucosyllactose Supplementation Improves GutBrain Signaling and Diet-Induced Obese Phenotype and Changes the Gut Microbiota in High Fat-Fed Mice Nutrients 2020, 12, 1003; doi:10.3390/nu12041003