HMO & BRAIN HEALTH
Human milk oligosaccharide supports brain functions directly through:
- Memory improvement
by strengthening synapses and LTP (long-term potentiation) in the hippocampus. - Brain development
when comparing children who were fed beast milk or HMO supplemented formula against their non supplemented peers. - Protect against brain damage by stroke and aiding brain recovery
as published in research papers
Gut-brain connection
Did you know that microorganisms in the intestines help the brain and gut communicate?
This is known as the Gut-brain connection! This is might also be the reason why we get indigestion when we are stressed or have a lot to think about. And when we have indigestion, chances are that we might also have a headache!
Human Milk Oligosaccharide can play a part in alleviating this! 95% of our serotonin, the neurotransmitter in charge of emotions, sleep etc, is produced in the gut! Human Milk Oligosaccharide stimulates the production of tryptophan, which serotonin is made from!
References
- Brain ganglioside and glycoprotein sialic acid in breastfed compared with formula-fed infants American Journal of Clinical Nutrition, 2003
- Fucose and fucosyllactose enhance in-vitro hippocampal long-term
potentiation
Brain Research 725 (1996) 276-280 - Effects of a human milk oligosaccharide, 2′-fucosyllactose, on hippocampal long-term
potentiation and learning capabilities in rodents
Journal of Nutritional Biochemistry 26 (2015) 455–465 - 2′-Fucosyllactose Attenuates Particulate Matter-Induced Inflammation
via Inhibition of Hypoxia-Inducible Factor in Keratinocytes
Biol. Pharm. Bull. 42, 1620–1627 (2019)
- Influence of 2'-fucosyllactose and galacto-oligosaccharides on the growth
and adhesion of Streptococcus mutans
British Journal of Nutrition (2020), 124, 824–831
- 2’-fucosyllactose Supplementation Improves GutBrain Signaling and Diet-Induced Obese Phenotype and Changes the Gut Microbiota in High Fat-Fed Mice
Nutrients 2020, 12, 1003; doi:10.3390/nu12041003